Endocrine Abstracts

Introduction: Acromegaly is a rare, chronic disease characterized by increased secretion of growth hormone, most commonly by autonomous adenoma of the anterior pituitary. Mortality is 2–3 times higher than in general population. So that, it is vital to achieve biochemical cure. We present a case in which patient was successfully treated with stereotactic radiotherapy (SRT)- CyberKnife and preserved pituitary function.Case report: A 39-years old men ...

Introduction: Acromegaly is a disease caused by excessive secretion of growth hormone and subsequently insulin growth factor 1. It is believed that this oversecretion can cause increased prevalence of nodular goiter and thyroid cancer. However, the amount of studies comparing acromegalic patients with control groups is low. The aim of the study was to assess the prevalence of thyroid lesions in patients with acromegaly in comparison with age and sex-matched control group.<...

Introduction: Hyperparathyroidism during pregnancy is a serious problem. Appropriate management is a matter of debate. We would like to present cases in which, PHP was diagnosed in completely different circumstances, though end up with various pregnancy outcomes.Case report: First patient was 29-year-old women in 21th week of her second pregnancy admitted to our ward due to suspected relapse of Graves’ disease and possible adrenal dysfunction. She p...

Introduction: While, both quality and accessibility to novel imaging technics rises, we observe a surge in detection of adrenal masses. Those tumors are accidentally found in ~ 0.4% of ultrasonographies and in 4% of computed tomography scans (CT) conducted due to other indications. In spite of high prevalence of those lesions approach to their diagnosis, follow-up and treatment is still controversial. High financial costs and possible adverse effect on health connected with th...

Purpose: Acromegaly is a disease characterized by the excessive secretion of GH. Clinically, it is manifested by overgrowth of tissues and internal organs, which leads to characteristic phenotype. Patients with active acromegaly usually have impaired glucose metabolism. It significantly improves after achieving remission of the disease. Adversely, disturbances in lipid profile are not altering. Moreover, these parameters are even worse in successfully treated patients. Ghrelin...

Introduction: Despite numerous studies, the biological association between chronic lymphocytic thyroiditis (CLT) and differentiated thyroid cancer (DTC) has not been elucidated yet. The aim of the study was to assess whether the presence of CLT exerts any influence on clinical or histological presentation of DTC.Materials and methods: Complete medical records of 907 consecutive patients with DTC treated at a single tertiary care department of endocrinolo...